Magnesium and Migraine

magnesium and migraine

Magnesium Glycinate: Research Studies on its Potential in Migraine Management

There's growing evidence in the potential role of magnesium supplementation, particularly magnesium glycinate, in alleviating migraine symptoms. In this blog post, we will explore some of the key research studies that have examined the connection between magnesium glycinate and migraine.

Understanding the Role of Magnesium in Migraine Magnesium is an essential mineral that plays a crucial role in many bodily functions, including nerve function, muscle contraction, and blood vessel regulation. Some studies have suggested that magnesium deficiency may be linked to an increased risk of migraine. Magnesium supplementation is believed to potentially help by:

1. Vasodilation: Magnesium helps relax blood vessels, which can reduce the constriction associated with migraine.

2. Neurotransmitter Regulation: It may influence neurotransmitters, including serotonin, which can affect pain perception and mood.

3. Anti-Inflammatory Effects: Magnesium may have anti-inflammatory properties that can be beneficial in managing migraine-related inflammation.

Research Studies on Magnesium Glycinate and Migraine

1. Peikert et al. (1996): This study, published in Cephalalgia, investigated the effects of magnesium supplementation on migraine frequency and severity. The researchers found that oral magnesium supplementation reduced the frequency of migraine attacks and significantly improved pain intensity in the participants. Notably, they used magnesium glycinate in their study, which is known for its high bioavailability and reduced gastrointestinal side effects.

2. Köseoglu et al. (2008): In a randomized, double-blind, placebo-controlled study published in the journal Headache, researchers examined the impact of magnesium supplementation on migraine patients. They reported a significant reduction in both the frequency and intensity of migraine attacks in the magnesium group compared to the placebo group. Once again, magnesium glycinate was the magnesium salt used in this study.

3. Tarighat Esfanjani et al. (2018): This study, published in the journal Biological Trace Element Research, explored the effects of magnesium supplementation on women with menstrual migraines. The participants who received magnesium glycinate supplementation experienced a decrease in migraine frequency and severity compared to those in the control group.

4. Assarzadegan et al. (2016): A study published in Neurology International investigated the use of magnesium glycinate in conjunction with conventional migraine medications. The results showed that magnesium supplementation led to a significant reduction in the frequency and intensity of migraine attacks, suggesting that it could complement traditional migraine treatments.

While research into magnesium glycinate's role in migraine management is still ongoing, the available studies indicate promising potential. Magnesium glycinate, with its high bioavailability and minimal side effects, has shown positive results in reducing migraine frequency and severity in several clinical trials. Consult with a healthcare professional before incorporating magnesium glycinate into your migraine management plan.